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Term Definition
IHC

A technique used to identify specific molecules in different kinds of tissue. The tissue is treated with antibodies that bind the specific molecule. These are made visible under a microscope by using a color reaction, a radioisotope, colloidal gold, or a fluorescent dye. Immunohistochemistry is used to help diagnose diseases, such as cancer, and to detect the presence of microorganisms. It is also used in basic research to understand how cells grow and differentiate (become more specialized). Also called immunohistochemistry.

Ileostomy

An opening into the ileum, part of the small intestine, from the outside of the body. An ileostomy provides a new path for waste material to leave the body after part of the intestine has been removed.

Immune system

The complex group of organs and cells that defends the body against infections and other diseases.

Immunocompromised

Having a weakened immune system caused by certain diseases or treatments.

Immunodeficiency

The decreased ability of the body to fight infections and other diseases.

Immunohistochemistry

A technique used to identify specific molecules in different kinds of tissue. The tissue is treated with antibodies that bind the specific molecule. These are made visible under a microscope by using a color reaction, a radioisotope, colloidal gold, or a fluorescent dye. Immunohistochemistry is used to help diagnose diseases, such as cancer, and to detect the presence of microorganisms. It is also used in basic research to understand how cells grow and differentiate (become more specialized). Also called IHC.

Immunophenotyping

A process used to identify cells, based on the types of antigens or markers on the surface of the cell. This process is used to diagnose specific types of leukemia and lymphoma by comparing the cancer cells to normal cells of the immune system.

Immunosuppression

Suppression of the body's immune system and its ability to fight infections and other diseases. Immunosuppression may be deliberately induced with drugs, as in preparation for bone marrow or other organ transplantation, to prevent rejection of the donor tissue. It may also result from certain diseases such as AIDS or lymphoma or from anticancer drugs.

Immunosuppressive therapy

Therapy used to decrease the body's immune responses, such as drugs given to prevent transplant rejection.

Immunotherapy

Treatment to boost or restore the ability of the immune system to fight cancer, infections, and other diseases. Also used to lessen certain side effects that may be caused by some cancer treatments. Agents used in immunotherapy include monoclonal antibodies, growth factors, and vaccines. These agents may also have a direct antitumor effect. Also called biological therapy, biotherapy, biological response modifier therapy, and BRM therapy.

Immunotoxin

An antibody linked to a toxic substance. Some immunotoxins can bind to cancer cells and kill them.

Impotence

In medicine, refers to the inability to have an erection of the penis adequate for sexual intercourse. Also called erectile dysfunction.

IMRT

A type of 3-dimensional radiation therapy that uses computer-generated images to show the size and shape of the tumor. Thin beams of radiation of different intensities are aimed at the tumor from many angles. This type of radiation therapy reduces the damage to healthy tissue near the tumor. Also called intensity-modulated radiation therapy.

In vitro

In the laboratory (outside the body). The opposite of in vivo (in the body).

In vivo

In the body. The opposite of in vitro (outside the body or in the laboratory).

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